Skip to main content
Delfa

← All assets

Umibecestat

3 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

3

Ongoing

0

Recruiting

0

Completed

1

Sites

282

Countries

25

Endpoints

92

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 92 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
1
Phase 2/3
2

Trials by status

Completed
1
Terminated
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Amyloid biomarkers
22
Global cognition
20
Safety / tolerability / PK
12
Memory
8
Neuroimaging
8
Other (unclassified)
8
Behavior / neuropsychiatric
4
Tau biomarkers
4
Neurodegeneration biomarkers
4
Fluid / digital biomarkers
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 14 of 92 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Mini-Mental State Examination (MMSE)Cognition

4

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

4

Neurofilament light (NfL)Neurodeg.

4

Amyloid PET CentiloidAmyloid

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

3 of 3

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
GS2A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

Umibecestat

Alzheimer’s disease

Amyloid biomarker required (PET/CSF)Ph 2/3Terminated194Mar 2020-results
GS1A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

CAD106, Umibecestat

Alzheimer’s disease

MMSE ≥24Ph 2/3Terminated129Apr 2020-results
NCT02576639Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age

Umibecestat

Alzheimer’s disease

Age 60-80Ph 2Completed11Mar 2016-results

Showing 1-3 of 3 trials