Lead sponsor
AbbVie
15 Alzheimer’s disease and related dementias trials led. Source: ClinicalTrials.gov, as of July 21, 2026.
15
Trials led
1
Ongoing
2,077
Total enrollment
273
Sites
Distinct sites across this sponsor's lead trials. A site running several of them counts once, matching the map. Total enrollment sums each trial's reported enrollment, whether planned or actual.
Portfolio
How this sponsor's trials break down
Trials by phase
Phase 1
6
Phase 1/2
1
Phase 2
7
Not applicable
1
Trials by status
Recruiting
1
Completed
7
Terminated
6
Unknown
1
Trials led
TrialEligibility highlightPhaseStatusEnrollment
A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Participants With Early Alzheimer's DiseaseAlzheimer's diseasePh 2Completed453
A Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Subjects With Progressive Supranuclear Palsy (PSP)Study partner/caregiver requiredPh 2Terminated378
An Extension Study of ABBV-8E12 in Early Alzheimer's Disease (AD)Study partner/caregiver requiredPh 2Terminated364
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's DiseaseAlzheimer's diseasePh 1/2Recruiting210
An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)Study partner/caregiver requiredPh 2Terminated142
A Study to Assess Safety of ABBV-916 and How Intravenous ABBV-916 Moves Through Body and Affects Brain Amyloid Plaque Clearance in Adult Participants (Aged 50-90 Years) With Early Alzheimer's DiseaseAlzheimer's diseasePh 2Completed106
A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy ParticipantsAge 18-40Ph 1Completed53
A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related ApathyMultiple dementia etiologiesPh 2Terminated41
Safety, Tolerability, and Pharmacokinetics of ABT-354 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase InhibitorsAlzheimer's diseasePh 1Completed20
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ABT-957 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitorsmild-to-moderate ADPh 1Terminated19
A Multiple Dose Trial of Emraclidine in Elderly Participants and in Participants With Dementia Due to Alzheimer's DiseaseAlzheimer's diseasePh 1Completed17
Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive ImpairmentMCI due to ADPh 1Terminated8