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Oral · GLP-1 agonist

Ecnoglutide (XW004)

2 trials in this program. Source: ClinicalTrials.gov, as of July 1, 2026.

Distinct formulations of the same molecule

This molecule is developed in parallel as separate programs. They are not competing therapies (they share the same active drug) but differ by formulation, route, and developer. Trials below are labeled with their program code.

Trials

2

Active

1

Recruiting

1

Completed

1

Sites

2

Countries

2

Endpoints

13

Composite endpoints

1

Distinct sites and countries across this program's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 1/2
1

Trials by status

Recruiting
1
Completed
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Weight & body composition
6
Safety / tolerability / PK
4
Glycemic / diabetes
2
Cardiometabolic biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Treatment-emergent AEs (any)Safety/PK

2

Body weight, absolute change (kg)Weight

1

BMI, changeWeight

1

Waist circumference, changeWeight

1

Fasting glucose, changeGlycemic

1

Immunogenicity (ADA)Safety/PK

1

Trials

Trials for XW004

Every trial for this program, with the same search, filters, and sort as the Trials tab.

2 of 2

Asset / PopulationKey I/E criterionEvidence
NCT05184322XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults

Ecnoglutide (XW004)

Healthy volunteers, Obesity / overweight

BMI 22-32Ph 1Completed1Jul 2024
NCT07243171A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity

Ecnoglutide (XW004)

Obesity / overweight

BMI 24-35Ph 1/2Recruiting1Aug 2026