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Subcutaneous · GLP-1 agonist

Albiglutide

39 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

39

Active

3

Recruiting

0

Completed

31

Sites

1,375

Countries

41

Endpoints

530

Composite endpoints

43

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
8
Phase 2
6
Phase 3
15
Phase 4
6
Not applicable
4

Trials by status

Not yet recruiting
1
Active, not recruiting
2
Completed
31
Terminated
3
Withdrawn
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Glycemic / diabetes
190
Safety / tolerability / PK
175
Weight & body composition
39
Cardiometabolic biomarkers
27
Cardiovascular outcomes
23
Renal / kidney
23
Other clinical outcomes
18
Patient-reported / QoL
16
Other (unclassified)
15
Heart failure
3
MASH / liver
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

50

Fasting glucose, changeGlycemic

38

Body weight, absolute change (kg)Weight

37

HbA1c <6.5% achievementGlycemic

23

HbA1c <7.0% achievementGlycemic

16

Documented hypoglycemiaSafety/PK

14

Postprandial glucoseGlycemic

11

Plasma concentration (steady state)Safety/PK

9

Heart rate, changeBiomarker

8

Treatment-emergent AEs (any)Safety/PK

8

Serious AEs (any)Safety/PK

7

AUC₀–∞Safety/PK

7

Discontinuation due to AESafety/PK

6

C-peptide AUCGlycemic

5

NauseaSafety/PK

5

Immunogenicity (ADA)Safety/PK

5

Expanded / custom MACE compositeCV

4

eGFR, changeRenal

4

CmaxSafety/PK

4

All-cause deathCV

3

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

39 of 39

Asset / PopulationKey I/E criterionEvidence
NCT02465515Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Albiglutide

Cardiovascular disease, Type 2 diabetes

Established CVDPh 4Completed607Feb 20187results
NCT00838903Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed386Jan 20121results
NCT00839527A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed358Jan 20123results
NCT00838916A Study to Determine the Safety and Efficacy of Albiglutide in Patients With Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed337Jan 20124results
NCT00849056Safety and Efficacy of Albiglutide in Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed331Nov 20111results
NCT00849017Safety and Efficacy Study of Albiglutide in Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed262Nov 20114results
NCT01098539A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.

Albiglutide

Renal impairment, Type 2 diabetes

HbA1c 7-10%Ph 3Completed218Nov 20122results
NCT00976391A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine

Albiglutide

Type 2 diabetes

HbA1c ≤7%Ph 3Completed209Oct 20111results
NCT01128894A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.

Albiglutide, Liraglutide

Type 2 diabetes

HbA1c 7-10%Ph 3Completed173Sep 20111results
NCT00518115Out-Patient Study in Patients With Type 2 Diabetes Mellitus Who Are Taking no Diabetes Medication or Metformin Only

Albiglutide, Exenatide

Type 2 diabetes

BMI 20-40Ph 2Completed163May 20082results
NCT02229227Safety and Efficacy of Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine Subjects With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI ≤40Ph 3Completed157Jul 20171results
LixiLan-GEfficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period

Albiglutide, Dulaglutide, Exenatide, GLP-1 / incretin class catch-all, Liraglutide, Lixisenatide

Type 2 diabetes

Ph 3Completed124May 20185results
NCT01733758A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)

Albiglutide, Liraglutide

Type 2 diabetes

BMI 17-40Ph 3Completed74Jun 2014results
NCT02683746Safety and Efficacy Study of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI ≤40Ph 3Completed70Apr 20171results
NCT01777282A Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Oral Monotherapy Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI 17-40Ph 3Completed49Jan 20151results
NCT02284009Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus

Albiglutide

Type 1 diabetes

BMI ≤32Ph 2Completed32Oct 20171results
NCT01098461Dose Ranging Study of Albiglutide in Japanese Subjects

Albiglutide

Type 2 diabetes

BMI 18-35Ph 2Completed30May 20112results
NCT01357889Pharmacokinetics/Pharmacodynamics of Albiglutide

Albiglutide

Type 2 diabetes

BMI 20-45Ph 2Completed30Oct 20121results
NCT02750930Extension to Study 200952 to Evaluate the Long-term Safety, Tolerability and Pharmacodynamics of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus Subjects

Albiglutide

Type 2 diabetes

Ph 4Terminated27Mar 2017results
NCT00938158A Study of the Pharmacokinetics of Albiglutide in Normal and Renally Impaired Subjects.

Albiglutide

Renal impairment, Type 2 diabetes

HbA1c 6-10.5%Ph 1Completed7Apr 20112
NCT00354536In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

Ph 2Completed5Sep 20061
NCT03015519A Study to Evaluate Pharmacokinetics, Safety and Efficacy of Albiglutide in Pediatric Subjects With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

HbA1c ≤10%Ph 3Withdrawn3Apr 2020
NCT02793154An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects

Albiglutide, Exenatide

Type 2 diabetes

BMI 2-35Ph 4Terminated2Mar 2017results
CER-4-T2DComparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

Albiglutide, Dulaglutide, Exenatide, Liraglutide, Lixisenatide, Semaglutide

Type 2 diabetes

Active, not recruiting1May 2026
NCT06449235Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh

Albiglutide, Dulaglutide, Exenatide, GLP-1 / incretin class catch-all, Liraglutide, Lixisenatide, Semaglutide

Type 2 diabetes

HbA1c 7-10%Ph 4Not yet recruiting1Apr 2025
DASH-CKMHUsing Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)

Albiglutide, Dulaglutide, Exenatide, Liraglutide, Lixisenatide, Semaglutide, Tirzepatide

Metabolic syndrome

Active, not recruiting1Jun 2029
NCT00537719Scintigraphy Study to Assess Gastric Emptying in Healthy Subjects Given GSK716155 or Placebo.

Albiglutide

Healthy volunteers

BMI 20-32Ph 1Completed1Apr 20081
NCT01077505An Evaluation of the Pharmacokinetics of an Oral Contraceptive (Brevicon) When Co-administered With Albiglutide .

Albiglutide

Healthy volunteers

BMI 19-30Ph 1Completed1Nov 20102
NCT01147692A Drug Interaction Study of Simvastatin and Albiglutide

Albiglutide

Healthy volunteers

BMI ≤30Ph 1Completed1Aug 20101
NCT01147718A Drug Interaction Study of Albiglutide and Digoxin

Albiglutide

Healthy volunteers

BMI ≤30Ph 1Completed1Nov 20102
NCT01147731A Drug Interaction Study With Albiglutide and Warfarin

Albiglutide

Healthy volunteers

BMI ≤30Ph 1Completed1Sep 20102
NCT01475734Albiglutide Glucose Clamp Study in Subjects With Type 2 Diabetes

Albiglutide

Obesity / overweight, Type 2 diabetes

BMI 28-40Ph 2Completed1Jul 20122results
NCT02496221A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects

Albiglutide

Healthy volunteers

BMI 2-30Ph 4Completed1Oct 20151results
NCT02660736Bioequivalence Study of Two Albiglutide Drug Products in Healthy Adult Subjects

Albiglutide

Healthy volunteers

BMI ≥18Ph 1Completed1Aug 20161
NCT02802514A Study Comparing the Effect of Albiglutide With Exenatide on Regional Brain Activity Related to Nausea in Healthy Subjects

Albiglutide, Exenatide

Healthy volunteers

Healthy volunteersPh 4Terminated1Aug 2017results
NCT02846233Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?

Albiglutide, Dulaglutide, GLP-1 / incretin class catch-all

Obesity / overweight, Type 2 diabetes

BMI ≥30Not applicableCompleted1Dec 20183results
NCT03492580A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease

Albiglutide, Dulaglutide, Exenatide, GLP-1 / incretin class catch-all, Liraglutide, Lixisenatide

Cardiovascular disease, Type 2 diabetes

Established CVDCompleted1Apr 2018
NCT01406262Albiglutide Thorough ECG Study in Healthy Volunteers

Albiglutide

Healthy volunteers

BMI 18-30Ph 1Completed0Dec 20111
NCT02229240Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI ≤40Ph 3Withdrawn0Dec 2015